Chemico-Biological Interactions publishes research reports and review articles that examine the molecular, cellular, and/or biochemical basis of toxicologically relevant outcomes. Special emphasis is placed on mechanisms associated with interactions between chemicals and biological systems. Outcomes may include all traditional endpoints caused by synthetic or naturally occurring chemicals, both in vivo and in vitro. Endpoints of interest include, but are not limited to, carcinogenesis, mutagenesis, respiratory toxicology, neurotoxicology, reproductive and developmental toxicology, and immunotoxicology.
The journal aims to elucidate the overlap between the chemical and biological sciences. Chemistry & Biodiversity demonstrates how chemistry can contribute to our understanding of biodiversity with the ultimate goal of benefiting from our preserving nature. Chemistry & Biodiversity publishes articles on all aspects of biodiversity studied at the molecular and macromolecular levels.
Chemistry and Physics of Lipids publishes research papers and review articles in the field of molecular biology which emphasise chemical and physical aspects of lipids. Accordingly, the journal covers: advances in synthetic and analytical lipid methodology; chemical and physical characterisation of isolated structures; thermodynamics, phase behaviour, topology and dynamics of lipid assemblies; physicochemical studies into lipid-lipid and lipid-protein interactions in lipoproteins and in natural and model membranes; movement of lipids within, across and between membranes; intracellular lipid transfer; structure-function relationships and the nature of lipid-derived second messengers; chemical, physical and functional alterations of lipids induced by free radicals; and the role of lipids in the regulation of membrane-dependent biological processes.
ChemMedChem on its way to become a premier journal at the interface of chemistry, biology and medicine. Its mission is to integrate the wide and flourishing field of medicinal and pharmaceutical sciences, ranging from drug design and discovery to drug development and delivery, from molecular modeling to combinatorial chemistry, from target validation to lead generation and ADMET studies—to name just a few topics.
Cholesterol is a peer-reviewed, open access journal that publishes original research articles, review articles, and clinical studies related to all aspects of cholesterol.
Chromosome Research provides for the rapid publication of high quality papers covering all aspects of chromosome and nuclear biology. Its editors welcome accounts of experimental studies of chromosome organization, function and behaviour. The journal is also pleased to publish studies in genomics, both functional and comparative, and studies in which karyology has helped to resolve difficult taxonomic problems or provide clues to fundamental mechanisms of genome and karyotype evolution. Straightforward karyotype descriptions are not normally accepted for publication in Chromosome Research.
Chromosomology is a field that spans all living organisms and one that exploits, more than almost any other, the comparative approach to biological research. In this sense the editors consider that research on human, animal, plant, yeast and other microbial systems can profitably share a common outlet in our journal.
Clinical Science was originally founded as Heart by Thomas Lewis in 1908 and celebrated 100 years of publishing excellence in clinical investigation in 2008. The Journal publishes papers in the field of translational science and medicine, defined as the whole range of biochemical, physiological, immunological and other approaches that may have relevance to disease in humans, particularly those which explore integrative biology of systems and pathways and the translation of molecular mechanisms to clinical applications.
Major subject areas covered include: Purification and analysis; Sequencing and amino acid sequences; Crystallography and crystal structures; Structure prediction; Spectroscopy; Protein dynamics; Protein-ligand interaction; Protein engineering and design; Protein chemistry; Protein synthesis; Active site structures; Enzyme specificity; Enzyme mechanism; Enzyme kinetics; Enzyme regulation; Oxidoreductive enzymes; Transferases; Hydrolytic enzymes; Lyases; Isomerases; Synthetases; Haem proteins; Nuclear proteins; Contractile proteins; Membrane proteins.
The subject of chemical biology is divided into themed sections which are reviewed regularly to keep them relevant. For 2009 they are: Bioinorganic chemistry; Biocatalysis and biotransformation; Molecular Diversity; Next-generation therapeutics; Mechanisms; Analytical techniques; Model systems; Biopolymers; Omics.